Insufficient synthesis of von Willebrand factor, a protein involved in blood coagulation
Gene involved VWF
Mutation tested c.7142C>T (vWD1)
Transmission mode : Autosomal recessive
Publication : Gentilini and Turba. (2013). Two novel real-time PCR methods for genotyping the von Willebrand disease type I mutation in Doberman Pinscher dogs.
Gene involved VWF
Mutation tested c.4937A>G (VWD2)
Transmission mode : Autosomal recessive
Publication : Kramer et al. (2004). A von Willebrand's factor genomic nucleotide variant and polymerase chain reaction diagnostic test associated with inheritable type-2 von Willebrand's disease in a line of german shorthaired pointer dogs.
Gene involved VWF
Mutation tested c.264delC (VWD3)
Transmission mode : Autosomal recessive
Publication : Venta et al. (2000). Mutation Causing von Willebrand’s disease in Scottish Terriers.
Gene involved VWF
Mutation tested c.937delT (VWD3)
Transmission mode : Autosomal recessive
Publication : Venta et al. (1998). DNA encoding canine von Willebrand factor and methods of use.