Insufficient synthesis of von Willebrand factor, a protein involved in blood coagulation
Gene involved
VWF
Mutation tested
c.7142C>T
(vWD1)
Transmission mode : Autosomal recessive
Publication : Gentilini and Turba. (2013). Two novel real-time PCR methods for genotyping the von Willebrand disease type I mutation in Doberman Pinscher dogs.
Gene involved
VWF
Mutation tested
c.4937A>G
(VWD2)
Transmission mode : Autosomal recessive
Publication : Kramer et al. (2004). A von Willebrand's factor genomic nucleotide variant and polymerase chain reaction diagnostic test associated with inheritable type-2 von Willebrand's disease in a line of german shorthaired pointer dogs.
Gene involved
VWF
Mutation tested
c.264delC
(VWD3)
Transmission mode : Autosomal recessive
Publication : Venta et al. (2000). Mutation Causing von Willebrand’s disease in Scottish Terriers.
Gene involved
VWF
Mutation tested
c.937delT
(VWD3)
Transmission mode : Autosomal recessive
Publication : Venta et al. (1998). DNA encoding canine von Willebrand factor and methods of use.