L-2-Hydroxyglutaric Aciduria

Gene involved
L2HGDH

Mutation tested
c.1297T>C et c.1299C>T

Transmission mode : Autosomal recessive

Publication : Penderis et al. (2007). L_2_hydroxyglutaric aciduria: characterisation of the molecular defect in a spontaneous canine model.

Concerned breeds :

Gene involved
L2HGDH

Mutation tested
c.1A>G

Transmission mode : Autosomal recessive

Publication : Farias et al. (2012). A L2HGDH initiator methionine codon mutation in a Yorkshire terrier with L-2-hydroxyglutaric aciduria.
Sanchez-Masian et al. (2012). L-2-hydroxyglutaric aciduria in two female Yorkshire terriers.

Concerned breeds :