Factor VII deficiency, which is a protein involved in the metabolism of blood clotting, leading to mild clotting disorders
Symptoms Asymptomatic or bleeding of gums during baby teeth loss, nosebleeds, bruising, bleeding that may be prolonged after surgery or trauma.
Gene involved F11
Mutation tested c.1546G>A
Transmission mode : Autosomal recessive Age of onset : From birth
Publication : Kuder et al. (2022). A common missense variant causing factor XI deficiency and increased bleeding tendency in Maine Coon cats.