Congenital Myasthenic Syndrome

Gene involved
CHRNE

Mutation tested
c.633_634insC

Transmission mode : Autosomal recessive

Publication : Rinz et al. (2015). A CHRNE frameshift mutation causes congenital myasthenic syndrome in young Jack Russell Terriers.

Gene involved
COLQ

Mutation tested
c.1010T>C

Transmission mode : Autosomal recessive

Publication : Rinz et al, (2014). A COLQ missense mutation in Labrador Retrievers having congenital myasthenic syndrome.

Gene involved
COLQ

Mutation tested
c.880G>A

Transmission mode : Autosomal recessive

Publication : Tsai et al. (2020). Congenital myasthenic syndrome in Golden Retrievers is associated with a novel COLQ mutation.

Concerned breeds :