Gene involved ITGB2
Mutation tested c.107G>C (CLAD)
Transmission mode : Autosomal recessive
Publication : Kijas et al. (1999). A missense mutation in the beta-2 integrin gene (ITGB2) causes canine leukocyte adhesion deficiency.
Gene involved FERMT3
Mutation tested c.1349_1350insAAGACGG CTGCC (LAD3)
Transmission mode : Autosomal recessive
Publication : Boudreaux et al. (2010). A mutation in the canine Kindlin-3 gene associated with increased bleeding risk and susceptibility to infections.