Amelogenesis Imperfecta

Gene involved
ENAM

Mutation tested
c.716C>T

Transmission mode : Autosomal recessive

Publication : Hytönen et al. (2019). Canine models of human amelogenesis imperfecta: identification of novel recessive ENAM and ACP4 variants.

Gene involved
ACP4

Mutation tested
c.1189dupG

Transmission mode : Autosomal recessive

Publication : Hytönen et al. (2019). Canine models of human amelogenesis imperfecta: identification of novel recessive ENAM and ACP4 variants.

Concerned breeds :

Gene involved
SCL24A4

Mutation tested
c.1530_1531insCTGGGCAT GTGCGTGCTGGCC

Transmission mode : Autosomal recessive

Publication : Pedersen et al. (2017). An autosomal recessive mutation in SCL24A4 causing enamel hypoplasia in Samoyed and its relationship to breed-wide genetic diversity.

Concerned breeds :

Gene involved
ENAM

Mutation tested
c.1992_1996delTTTCC

Transmission mode : Autosomal recessive

Publication : Gandolfi et al. (2013). Simple recessive mutation in ENAM is associated with amelogenesis imperfecta in Italian Greyhounds.

Concerned breeds :