Obstructed intraocular fluid drainage and increased intraocular pressure damaging the optic nerve and retinal cells
Symptoms Bilateral mild to moderate globe enlargement
Gene involved LTBP2
Mutation tested c.1998insGGAG
Transmission mode : Autosomal recessive Age of onset : Between 2 and 6 months old
Publication : Kuehn et al. (2016). A mutation in LTBP2 causes congenital glaucoma in domestic cats (Felis catus).