Determines the production or non-production of eumelanin (black, brown pigment)
Symptoms Wild allele E triggers the production of eumelanin.
Gene involved MC1R
Mutation tested c.250G>A (e)
Transmission mode : Autosomal recessive Age of onset : The final coat colour stabilises between 2 and 5 years old Specificity : Amber coat colour Remarcks : A cat born with an orange colour coat will not be affected by the mutation but may transmit it.
Publication : Peterschmitt et al. (2009). Mutation in the melanocortin 1 receptor is associated with amber colour in the Norwegian Forest Cat.
Gene involved MC1R
Mutation tested c.640_669del (ec)
Transmission mode : Autosomal codominant Age of onset : Progressive trait: the black pigments in the kitten fur will change to an amber colour. Specificity : Copal and Carnelian coat colours
Publication :
Abitbol et al. (2019). Copal, a new MC1R allele in the domestic cat.
Bychkova et al. (2020). A new mutation in the MC1R gene leads to unique carnelian color in Kurilian Bobtails.
Gene involved MC1R
Mutation tested c.439_441del (er)
Transmission mode : Autosomal recessive Age of onset : Progressive trait: the black pigments in the kitten fur will change to an redder colour. Specificity : Russet coat colour
Publication : Gustafson et al. (2017). Not another type of potato: MC1R and the russet coloration of Burmese cats.