Determines the distribution of pheomelanin (red pigment) and eumelanin (black pigment) in time and space
Symptoms
Alternating light and dark areas on the hair (tabby pattern). A non-agouti cat (solid colour) has hair without distinction of stripes.
Gene involved
ASIP
Mutation tested
c.122_123delCA
(a)
Transmission mode : Autosomal recessive
Age of onset : From birth
Specificity : Non-agouti (solid) hair
Publication : Eizirik et al. (2003). Molecular genetics and evolution of melanism in the cat family.
Gene involved
ASIP
Mutation tested
c.142T>C
(Apb)
Transmission mode : Autosomal dominant with incomplete penetrance
Age of onset : From birth
Specificity : Charcoal pattern
Remarcks : Expressed only in Apb/a heterozygous cat.
Publication : Gershony et al. (2014). Who's behind that mask and cape? The Asian leopard cat's Agouti (ASIP) allele likely affects coat colour phenotype in the Bengal cat breed.