Determines the distribution of pheomelanin (red pigment) and eumelanin (black pigment) in time and space
Symptoms Alternating light and dark areas on the hair (tabby pattern). A non-agouti cat (solid colour) has hair without distinction of stripes.
Gene involved ASIP
Mutation tested c.122_123delCA (a)
Transmission mode : Autosomal recessive Age of onset : From birth Specificity : Non-agouti (solid) hair
Publication : Eizirik et al. (2003). Molecular genetics and evolution of melanism in the cat family.
Gene involved ASIP
Mutation tested c.142T>C (Apb)
Transmission mode : Autosomal dominant with incomplete penetrance Age of onset : From birth Specificity : Charcoal pattern Remarcks : Expressed only in Apb/a heterozygous cat.
Publication : Gershony et al. (2014). Who's behind that mask and cape? The Asian leopard cat's Agouti (ASIP) allele likely affects coat colour phenotype in the Bengal cat breed.