HR Locus - Hypotrichosis

Significant reduction in the average numbers of follicles per hair follicle group

Symptoms
Sparse hair coat with roaning, implying full color and all white hairs.

Gene involved
HR

Mutation tested
c.2593C>T (hrCa)

Transmission mode : Autosomal recessive
Age of onset : From birth

Publication : Buckley et al. (2020). Werewolf, There Wolf: Variants in Hairless Associated with Hypotrichia and Roaning in the Lykoi Cat Breed.

Concerned breeds :

Gene involved
HR

Mutation tested
c.2243C>T (hrNC)

Transmission mode : Autosomal recessive
Age of onset : From birth

Publication : Buckley et al. (2020). Werewolf, There Wolf: Variants in Hairless Associated with Hypotrichia and Roaning in the Lykoi Cat Breed.

Concerned breeds :

Gene involved
HR

Mutation tested
c.1404+2delinsCAG (hrFr)

Transmission mode : Autosomal recessive
Age of onset : From birth

Publication : Buckley et al. (2020). Werewolf, There Wolf: Variants in Hairless Associated with Hypotrichia and Roaning in the Lykoi Cat Breed.

Concerned breeds :

Gene involved
HR

Mutation tested
c.2112G>A (hrTX)

Transmission mode : Autosomal recessive
Age of onset : From birth

Publication : Buckley et al. (2020). Werewolf, There Wolf: Variants in Hairless Associated with Hypotrichia and Roaning in the Lykoi Cat Breed.

Concerned breeds :

Gene involved
HR

Mutation tested
c.1255_1256dup (hrTN)

Transmission mode : Autosomal recessive
Age of onset : From birth

Publication : Buckley et al. (2020). Werewolf, There Wolf: Variants in Hairless Associated with Hypotrichia and Roaning in the Lykoi Cat Breed.

Concerned breeds :

Gene involved
HR

Mutation tested
c.3389insGACA (hrVA)

Transmission mode : Autosomal recessive
Age of onset : From birth

Publication : Buckley et al. (2020). Werewolf, There Wolf: Variants in Hairless Associated with Hypotrichia and Roaning in the Lykoi Cat Breed.

Concerned breeds :