Cancer affecting histiocytes, cells responsible for immune function. Development of tumours spread throughout several organs (spleen, lungs, liver, lymph nodes…)
Symptoms Weight loss, lethargy, anorexia, occasionally fever, cough and pale mucous membranes
Transmission mode : Polygenic and multifactorial
Publication : Hédan et al. (2020). Advances in the knowledge of the genetic bases of histiocytic sarcoma and the development of the genetic risk test SH and the online tool HSIMS.