Deficiency of factor VII, a protein involved in blood coagulation
Symptoms Mild bleeding disorder: excessive gingival haemorrhage during eruption of adult teeth, nose bleeding, skin bruising, prolonged bleeding after surgery or trauma
Gene involved F7
Mutation tested c.287G>A
Transmission mode : Autosomal recessive
Publication : Callan et al. (2006). A novel missense mutation responsible for factor VII deficiency in research Beagle colonies.