Gene involved
MC1R
Mutation tested
c.916C>T
(e)
Transmission mode : Autosomal recessive
Publication : Newton et al. (2000). Melanocortin 1 receptor variation in the domestic dog.
Gene involved
MC1R
Mutation tested
g.63695679C>G
(e2)
Transmission mode : Autosomal recessive
Publication : Dürig et al. (2018). Two MC1R loss-of-function alleles in cream-coloured Australian Cattle Dogs and white Huskies.
Gene involved
MC1R
Mutation tested
c.816_817delCT
(e3)
Transmission mode : Autosomal recessive
Publication : Dürig et al. (2018). Two MC1R loss-of-function alleles in cream-coloured Australian Cattle Dogs and white Huskies.
Gene involved
MC1R
Mutation tested
c.790A>G
(Em)
Transmission mode : Autosomal dominant
Publication : Schmutz et al. (2003). MC1R studies in dogs with melanistic mask or brindle patterns.
Gene involved
MC1R
Mutation tested
c.233G>T
(Eg)
Transmission mode : Autosomal dominant
Specificity : Domino/Grizzle coat colour
Publication : Dreger et al. (2010). A new mutation in MC1R explains a coat color phenotype in 2 “old” breeds: Saluki and Afghan Hound.
Gene involved
MC1R
Mutation tested
c.250G>A
(Eh)
Transmission mode : Autosomal dominant
Specificity : Sable coat colour
Publication : Honkanen et al. (2024). Canine coat color E locus updates: Identification of a new MC1R variant causing 'sable' coat color in English Cocker Spaniels and a proposed update to the E locus dominance hierarchy.
Gene involved
MC1R
Mutation tested
c.901C>T
(eA)
Transmission mode : Autosomal recessive
Age of onset : From birth
Specificity : Domino/Grizzle coat colour
Publication : Anderson et al. (2020). Comprehensive genetic testing combined with citizen science reveals a recently characterized ancient MC1R mutation associated with partial recessive red phenotypes in dog.