Build-up of cystine in the kidney which leads to kidney stones and urinary tract inflammation
Symptoms Difficulty in urinating, possible presence of blood in the urine. If left untreated, this disease can lead to kidney failure and the death of the dog.
Gene involved SLC7A9
Mutation tested c.881T>A
Transmission mode : Autosomal recessive Age of onset : Between 1 and 4 years old
Publication : Mizukami et al. (2016). Cystinuria associated with different SLC7A9 gene variants in the cat.