2,8-Dihydroxyadenine Urolithiasis

Gene involved
APRT

Mutation tested
c.260G>A

Transmission mode : Autosomal recessive

Publication : Furrow et al. (2014). An APRT mutation is strongly associated with and likely causative for 2,8-dihydroxyadenine urolithiasis in dogs.

Concerned breeds :
Chien Loup Américain
Chien Loup Européen
Chien Loup Tchécoslovaque
Old Inuit Dog

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